Josh L. Stern Assistant professor, University of Alabama, Birmingham

Josh L. Stern Assistant professor, University of Alabama, Birmingham

Josh L. Stern Assistant professor, University of Alabama, Birmingham Josh L. Stern Assistant professor, University of Alabama, Birmingham
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 *Contributed equally to manuscript                                                                        

  • Stern J.L., Hibshman G., Hu K., Ferrara S.E., Costello J., Kim W.J., Tamayo P., Cech, T.R., Huang F.W. Mesenchymal and MAPK Expression Signatures Associate with Telomerase Promoter Mutations in Multiple Cancers. Accepted. 04/07/2020. Molecular Cancer Research.  https://doi.org/10.1158/1541-7786.MCR-19-1244 


  • Stern J.L., Paucek R.D., Huang F.W., Ghandi M., Nwumeh R., Costello J., Cech T.R. Allele-specific DNA methylation and its interplay with repressive histone marks at promoter-mutant TERT genes. Cell Reports (2017).   doi.org/10.1016/j.celrep.2017.12.001  


  • Tong A.S.*, Stern J.L.*, Sfeir A., Kartawinata M., de Lange T. Zhu X-D., Bryan T.M. ATM and ATR Signalling Regulate the Recruitment of Human Telomerase to Telomeres. Cell Reports. 13, 1633-46 (2015).  doi.org/10.1016/j.celrep.2015.10.041 


  • Stern J.L., Theodorescu D., Vogelstein B., Papadopoulos N., Cech T.R. Mutation of the TERT promoter, switch to active chromatin, and monoallelic TERT expression in multiple cancers. Genes Dev. 29, 2219-24 (2015).   doi.org/10.1101/gad.269498.115 


  • Stern J.L., Zyner K.G., Pickett H.A., Cohen S.B., Bryan T.M. Telomerase recruitment requires both TCAB1 and Cajal bodies independently. Mol. Cell Biol. 32, 2384-95,(2012).   


  • Lasham, A., Samuel, W., Cao, H., Patel, R., Mehta, R., Stern, J.L., Reid, G., Woolley, A.G., Miller, L.D., Black, M.A., Shelling, A.N., Print, C.G., Braithwaite, A.W. YB-1, the E2F pathway, and regulation of tumor cell growth. J. National Cancer Inst., 104, 133-146 (2012). 


  • Harikrishnan K.N., Williamson, S.L., Minchenko, D., El-Osta, A., Stern, J.L., Christodoulou, J. Downstream targets of methyl CpG binding protein 2 and their abnormal expression in the frontal cortex of the human Rett syndrome brain. BMC Neuroscience, 11, art. no. 53 (2008). 


  • Harman, A.N., Kraus, M., Bye, C.R., Byth, K., Turville, S.G., Tang, O., Mercier, S.K., Nasr, N., Stern, J.L., Slobedman, B., Driessen, C., Cunningham, A.L. HIV-1-infected dendritic cells show 2 phases of gene expression changes, with lysosomal enzyme activity decreased during the second phase.  Blood, 114, 85-94 (2009). 


  • Stern, J.L., Bryan, T.M. Telomerase recruitment to telomeres. Cytogenetic and Genome Res., 122, 243-254 (2008).
     
  • Stern, J.L., Slobedman, B. Human cytomegalovirus latent infection of myeloid cells directs monocyte migration by up-regulating monocyte chemotactic protein-1. J. Immunology, 180, 6577-6585 (2008). 


  • Stern, J.L., Cao, J.Z., Xu, J., Mocarski, E.S., Slobedman, B. Repression of human cytomegalovirus major immediate early gene expression by the cellular transcription factor CCAAT displacement protein. Virology, 378, 214-225 (2008). 


  • Jenkins, C., Garcia, W., Godwin, M.J., Spencer, J.V., Stern, J.L., Abendroth, A., Slobedman, B. Immunomodulatory properties of a viral homolog of human interleukin-10 expressed by human cytomegalovirus during the latent phase of infection. J. Virology, 82, 3736-3750 (2008).


  • Harman, A.N., Wilkinson, J., Bye, C.R., Bosnjak, L., Stern, J.L., Nicholle, M., Lai, J., Cunningham, A.L. HIV induces maturation of monocyte-derived dendritic cells and Langerhans cells. J.  Immunology, 177,7103-7113 (2006). 


  • Slobedman, B.*, Stern, J.L.*, Cunningham, A.L., Abendroth, A., Abate, D.A., Mocarski, E.S. Impact of Human Cytomegalovirus Latent Infection on Myeloid Progenitor Cell Gene Expression.  J. Virology. 78, 4054-4062 (2004).


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